History of Anavar


Anavarwhich is also called the (Oxandrolone) is  originally developed by the Doctor Raphael Pappo by sing  the brand name of  Oxandrin, he used to worked for the Searle laboratories. He discovered  Anavar in 1964 which he said was for the treatment of multiple disease including those relating to the muscle.  In that point of time anabolic steroids were entirely unheard of within the general market.He was also a part of the founders of the first few range of oral steroids which had hit the bodybuilding arena.  In later times Searle was purchased by Pfizer and anavar was decided to be discontinued.

In early 80’s when AIDS epidemic began, it was Anavar and Anadrol (Oxymetholone) that were the only  prescribed drugs while treating the muscle wasting issues.

Working of Anavar

  • Anavar produces lean gains with very little water retention
  • It also increases strength.

·         para mantener la masa muscular (to maintain muscle mass )

Anavarbecame popular in the bodybuilder, athletes market as a recreational steroid with the publication “Muscle Media 2000” (the first national magazine to talk openly about steroids) which gaveAnavar the highest rating in regard to benefit to risk ratio. The magazine popularized anavar by stating that Anavargives benefits without toxicity .

Chemical formation

The scientific molecular structure of Anavar is  5-alpha-androstan-2-oxa-17 alpha-methyl-17 beta-ol-3-one.  While developing the formula, Raphael Pappo synthesized the drug by pulling out its molecular structure from dihydrotestosterone. The key difference is that an oxygen atom is known to replace the methylation and 2 carbon in the 17 position.  To be true Oxandrolone was developed to be a gentler Dianabol – more anabolic and less androgenic, hence erasing out many of the undesirable side effects. This was also done by replacing oxygen for the other elements which are generally present in dihydrotestosterone.  Applying this process, Pappo was successful in creating a steroid that has one of the lowest rates of androgenicity within a wide range of synthetic steroids.

Anavar is considered to be an useful drug on so many levels.  It seems to go against the definition of such drugs and the limitations attached to the use of the oral steroids.  You must have sometimes read about it being very “clean gains” and highly safe for the human use which does not or causes a very little side effect to your health conditions . You must be also aware that it is actually much safer unlike other the other available steroids in the market, which are normally used for treating problem like malnutrition and anemia, Anavar was originally prescribed mainly for victims who have had a burning  condition . In a random double-blind study on patients with 40% total body surface area burns  was conducted who were selected to receive standard burn care plus oxandrolone, or without oxandrolone.

  • Oxandrolone is used to help regain weight loss after surgery,
  • To come out severe trauma
  • To treat chronic infections.

·         para mantener la masa muscular (to maintain muscle mass )

Those who are  treated with oxandrolone showed quickened healing, improved body composition,preserved muscle mass and reduced catabolism and consequently lessened hospital stay time. Hence there is no wonder that it was of interest to bodybuilders!